Dear Karl, I hurt!
Unnecessary Pain

If radiation therapy is unavailable or if neurological signs worsen despite medical therapy, surgical decompression should be performed unless the patient is not a surgical candidate. Surgery is also indicated when a biopsy is needed, when the spine is unstable, when tumors have recurred after radiation therapy, or when compressing subdural or epidural hematoma or any abscess is present. After surgery for epidural metastases, patients should generally receive radiation therapy. (source in the main article)

Multiple sclerosis is a devastating, autoimmune neurodegenerative disease, involving myelin sheath degradation and inflammation of the brain and spinal cord. MS patients have neural cell membrane defects in these areas involving calcium ion up regulation of calpain and subsequent degradation of nerve tissue. Although MS therapies do exist today, they are considered only partially satisfactory due to lack of universal effectiveness and accompanying side effects. The Company's product candidate, NEURODUR, has been shown effective in animal models. NEURODUR combines the nerve cell targeting transport molecule, taurine, with the calpain inhibitor, leupeptin. NEURODUR data from MS mouse models are promising as they demonstrated a direct delivery to and positive impact on the brain and spinal cord. In an MS mouse model, brain inflammation was evident in the non-treated mice, but not in the NEURODUR treated mice. All of the NEURODUR treated mice lived while all of the non-treated mice died. [Source in the main article]