Click Here For Another Page of These Studies
NLM database Documents
Record 1 from database: MEDLINE
Return To Top
- Title
- Polyphenols from Bulgarian medicinal plants with anti-infectious activity.
- Author
- Ivancheva S; Manolova N; Serkedjieva J; Dimov V; Ivanovska N
- Address
- Botanical Institute, Bulgarian Academy of Sciences, Sofia.
- Source
- Basic Life Sci, 1992, 59:, 717-28
- Abstract
- Three Bulgarian medicinal plants--Geranium macrorrhizum L. and G. sanguineum L. (Geraniaceae), and Epilobium hirsutum L. (Onagraceae) were analyzed phytochemically. Different polyphenols like flavonoids and tannis have been found to be principal constituents of the plants. A series of water or alcohol extracts was obtained, and their anti-infectious activity was tested. A significant inhibitory effect of water-alcohol extract and of four fractions from the polyphenolic mixture of E. hirsutum on the reproduction of influenza viruses in vitro, in ovo, and in vivo was established. Four extracts from G. macrorrhizum and three extracts from G. sanguineum were studied for in vitro inhibition of the growth of some Gram-negative bacteria (Klebsiella pneumoniae, Proteus vulgaris, Escherichia coli, Pseudomonas aeruginosa), Gram-positive bacterium (Staphylococcus aureus), and fungus (Candida albicans). Some geranium extracts caused a strong increase of the survival rate in an infection with K. pneumoniae in mice. Augmentation of the nonspecific host resistance in relation to the influence of the extracts on the classical complement activation pathway was also studied.
- Language of Publication
- English
- Unique Identifier
- 93038462
- MeSH Heading (Major)
- Anti-Infective Agents|IP/*PD; Phenols|IP/*PD; Plants, Medicinal|*CH; Polymers|IP/*PD
- MeSH Heading
- Animal; Antifungal Agents|IP/PD; Antiviral Agents|IP/PD; Bacterial Infections|DT; Bulgaria; Chick Embryo; Complement Activation; Influenza|DT; Influenza A Virus, Human|DE; Mice; Mice, Inbred ICR; Mycoses|DT
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0090-5542
- Country of Publication
- UNITED STATES
Record 2 from database: MEDLINE
- Title
- Indigenous phytotherapy of gastrointestinal disorders in a lowland Mixe community (Oaxaca, Mexico): ethnopharmacologic evaluation.
- Author
- Heinrich M; Rimpler H; Barrera NA
- Address
- Institut fÂur Pharmazeutische Biologie, Albert Ludwigs UniversitÂat, Freiburg, F.R.G.
- Source
- J Ethnopharmacol, 1992 Feb, 36:1, 63-80
- Abstract
- Gastrointestinal disorders are one of the major health problems in developing countries. Sixty-five plants used popularly in the treatment of such disorders in a Mixe Indian community in Oaxaca (Mexico) and collected during a fieldstudy of 15 months are described. According to indigenous criteria a plant is used in the treatment of a certain illness because of the plant's characteristic smell and taste. Plants with astringent properties are particularly valued to treat diarrhoea and dysentery. Bitter, aromatic and bitter-aromatic plants are especially employed to treat gastrointestinal cramps and pain. Additionally, the efficacy of these plants was evaluated using ethnobotanical, phytochemical and pharmacologic information on the plants. The majority of the plants contain chemicals that may produce the effects desired by the Mixe. Frequently tannin-containing drugs are used to treat diarrhoea and dysentery. A large number of the plants used by the Mixe in the treatment of gastrointestinal pain contain essential oil or bitter principles. As a result of this evaluation, plants were selected which should be studied phytochemically and pharmacologically with priority, to evaluate further their potential in the treatment of gastrointestinal disorders.
- Language of Publication
- English
- Unique Identifier
- 92365397
- MeSH Heading (Major)
- Gastrointestinal Diseases|PS/*TH; Indians, Central American|*; Medicine, Traditional|*; Plants, Medicinal|*/CH/CL
- MeSH Heading
- Diarrhea|TH; Dysentery|TH; Human; Mexico; Pain|TH; Parasitic Diseases|TH; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 3 from database: MEDLINE
- Title
- Traditional botanical remedies on a small Caribbean island: Middle (Grand) Caicos, West Indies.
- Author
- Halberstein RA
- Address
- Department of Anthropology, University of Miami, Coral Gables, FL, USA.
- Source
- J Altern Complement Med, 1997 Fal, 3:3, 227-39
- Abstract
- A descriptive survey of 18 medicinal plants utilized on Middle (Grand) Caicos Island in the West Indies revealed that each species has multiple applications. Phytochemical constituents, ascertained from published sources, suggest pharmacological/physiological efficacy in the ethnomedical treatment of various disorders. Traditional preparation procedures may enhance the chemotherapeutic value of the plant derivatives, while at the same time reducing their potential toxicity. The majority of species used in Middle Caicos are also exploited in other cultures but often for very different purposes.
- Language of Publication
- English
- Unique Identifier
- 98090191
- MeSH Heading (Major)
- Medicine, Herbal|*; Plants, Medicinal|CH/CL/PH/*TU
- MeSH Heading
- Child; Female; Human; Infant; Male; Pregnancy; Support, Non-U.S. Gov't; West Indies
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 1075-5535
- Country of Publication
- UNITED STATES
Record 4 from database: MEDLINE
- Title
- A contribution to our knowledge of Leonurus L., i-mu-ts'ao, the Chinese motherwort.
- Author
- Hu S
- Address
- Source
- Am J Chin Med, 1976 Aut, 4:3, 219-37
- Abstract
- This article deals with the ethnobotanical aspects of the Chinese motherwort. Since time immemorial the Chinese people have used various parts of motherwort to meet different physical needs. By the time a written language was developed and the medical uses were recorded. , motherwort was treated as an article of superior quality. At present, under the name of i-mu-ts'ao, the plant is used for improving bloodflow both by official physicians and herbal practitioners throughout the country as well as by villagers in isolated areas. According to Chinese classical literature on materia medica, the early uses were limited to the parts of the plant which met the most obvious needs of the prehistorical people in their struggle for existence-food and pain reliever. Evidently, in their search for food, the ancient people found that the four nutlets contained in the dry and spinose calyx of the Chinese motherwort resemble the seasame seed in size and oil content. They gathered them and used them for food in similar manner as with the sesame. Consequently, they discovered the good effects to the eyesight, the improvement of strength, and the uplift of spirit. These discoveries led to the use of the seed of the species as an eye medicine for improving the eyesight, and as a tonic for the increase of strength and the elevation of spirit. Contagious skin diseases caused serious problems for the ancient people. The use of the leafy shoot for a bath to release the discomfort of itches and shingles was also recorded in the 42-word first medicinal record of the species in the earliest known Chinese materia medica-the Shen-nung pen-ts'ao-ching. Translators of the Chinese classics have included the records of i-mu-ts'ao. According to my knowledge, these works are all partial translations with the selections of the medicinal properties and the omissions on the methods of preparation. They have the outline and abandon the details. Consequently most of them are not clear. In order to provide complete information on the discoveries of the ancient Chinese people on the uses of i-mu-ts'ao, all the records up to the end of the sixteenth century are organized and translated under the following headings: (1) ecological and morphological observations; (2) preparations; (3) physical and therapeutical properties; (4) special prescriptions for internal and external uses-including pills for pregnant women, for mothers post partum, as an emmenagogue, and as a corrective agent, condensed liquid, powder, fresh juice, baby bath and washes, poultices, charred shoots, gargles, drops and cakes; (5) other economic uses-including cosmetics and food; and (6) etymology. The distribution of i-mu-ts'ao is significant in photogeography and in the nomenclature of the species. I-mu-ts'ao was purposely introduced from South China to Linnaeus in Sweden before the publication of the Species Plantarum in 1753. Linnaeus planted the seed in the botanical garden of the University of Uppsala...
- Language of Publication
- English
- Unique Identifier
- 77019301
- MeSH Heading (Major)
- Plants, Medicinal|*/AH/CL
- MeSH Heading
- Blood Circulation|DE; China; Female; Human; Male; Plant Extracts|PD; Pregnancy
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0090-2942
- Country of Publication
- UNITED STATES
Record 5 from database: MEDLINE
- Title
- Records of usage or assays in Phyllanthus (Euphorbiaceae). I. Subgenera Isocladus, Kirganelia, Cicca and Emblica.
- Author
- Unander DW; Webster GL; Blumberg BS
- Address
- Division of Population Science, Fox Chase Cancer Center, Philadelphia, PA 19111.
- Source
- J Ethnopharmacol, 1990 Oct, 30:3, 233-64
- Abstract
- References to either indigenous uses or the results of controlled assays are numerous for species of Phyllanthus (Euphorbiaceae). These citations have been arranged by subgenus, section, subsection and species and will be published as three separate papers, followed by a paper discussing the apparent clustering of some uses or effects within taxa. This paper, the first of the series, covers the subgenera Isocladus, Kirganelia, Cicca and Emblica.
- Language of Publication
- English
- Unique Identifier
- 91080573
- MeSH Heading (Major)
- Plants, Medicinal|*/AN/CL
- MeSH Heading
- Human; Medicine, Traditional; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 6 from database: MEDLINE
- Title
- Medicinal plants used for child's respiratory diseases in Zaire. Part I.
- Author
- Disengomoka I; Delaveau P
- Address
- Source
- J Ethnopharmacol, 1983 Sep, 8:3, 257-63
- Abstract
- Traditional Medicine, as practised by the populations of developing Countries such as ZaÁre, traditionally use mostly plants for various illnesses. Within 300 km radius around Kinshasa, 94 plants used by various tradipractitioners to treat respiratory diseases in children were collected. These plants are identified, and the writers underline the role the tradipractitioner plays in gathering ethno-botanical and ethno-pharmacognostic data.
- Language of Publication
- English
- Unique Identifier
- 84066342
- MeSH Heading (Major)
- Plants, Medicinal|*/CL; Respiratory Tract Diseases|*TH
- MeSH Heading
- Child; Democratic Republic of the Congo; Human
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 7 from database: MEDLINE
- Title
- Plant folklore: a tool for predicting sources of antitumor activity?
- Author
- Spjut RW; Perdue RE Jr
- Address
- Source
- Cancer Treat Rep, 1976 Aug, 60:8, 979-85
- Abstract
- The National Cancer Institute's record of "active plants" (extracts which showed a significant inhibitory effect in experimental tumor systems) was compared with plants reported in folklore to have medicinal or poisonous properties. The occurrence of active plants was found to be higher in plants reported in folk literature than in plants collected at random, suggesting a correlation between plants used in folklore and those with anticancer activity.
- Language of Publication
- English
- Unique Identifier
- 77046955
- MeSH Heading (Major)
- Folklore|*; Neoplasms|*DT; Plants, Medicinal|*/CL
- MeSH Heading
- Anthelmintics|TU; Antineoplastic Agents, Phytogenic; Human; Plants, Toxic; Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0361-5960
- Country of Publication
- UNITED STATES
Record 8 from database: MEDLINE
- Title
- Tabernaemontana L. (Apocynaceae): a review of its taxonomy, phytochemistry, ethnobotany and pharmacology.
- Author
- Van Beek TA; Verpoorte R; Svendsen AB; Leeuwenberg AJ; Bisset NG
- Address
- Source
- J Ethnopharmacol, 1984 Feb, 10:1, 1-156
- Abstract
- The taxonomy, phytochemistry, ethnobotany, and pharmacology of the genus Tabernaemontana L. (Apocynaceae) is reviewed. The genus is currently being revised taxonomically; most of the segregate genera are being reunited with it and the number of species that will ultimately be recognized will probably be about 100. All the names encountered in the chemical and ethnobotanical literature have been evaluated as far as possible, and a list is presented of the recognized species and their synonyms. The biogenesis and classification of the indole alkaloids found in Tabernaemontana species is set out and some problems in the determination of their stereochemistry are discussed. To facilitate access to the information, three lists have been compiled: the alkaloids in alphabetical order; the alkaloids in order of increasing molecular weight; and the alkaloids grouped according to their biogenetic classification, together with the species and plant part(s) in which they are known to occur. Biogenetic and chemotaxonomic aspects are briefly considered. A table of the non-alkaloidal constituents is also included. The ethnobotany of individual Tabernaemontana species is outlined and an overall assessment made. Likewise, information on the pharmacology of crude extracts and individual alkaloids from Tabernaemontana species has been assembled and appraised.
- Language of Publication
- English
- Unique Identifier
- 84189921
- MeSH Heading (Major)
- Plants, Medicinal|*/CL
- MeSH Heading
- Alkaloids|BI; Animal; Botany; Chemistry; Human; Medicine, Traditional; Plant Extracts|PD; Plants, Toxic
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 9 from database: MEDLINE
- Title
- Ethnopharmacologic investigation on tropane-containing drugs in Chinese solanaceous plants.
- Author
- Xiao PG; He LY
- Address
- Source
- J Ethnopharmacol, 1983 Jul, 8:1, 1-18
- Abstract
- The role of tropane-containing drugs derived from Solanaceae has long been recognized. This report deals with Chinese solanaceous plants, including historic, botanical, phytochemical, pharmacological and clinical aspects. Our investigation revealed that this kind of drug is constantly being confirmed to be of true therapeutic value; however, further studies are in order.
- Language of Publication
- English
- Unique Identifier
- 84038057
- MeSH Heading (Major)
- Plants, Medicinal|*/AN; Tropanes|*AN/PD
- MeSH Heading
- Animal; China; Human; Medicine, Chinese Traditional
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 10 from database: MEDLINE
- Title
- Plants used by Mexican traditional medicine with presumable sedative properties: an ethnobotanical approach.
- Author
- Tortoriello J; Romero O
- Address
- Unidad de InvestigaciÆon BiomÆedica del Sur, Centro de InvestigaciÆon de Plantas Medicinales, IMSS, Xochitepec, Morelos, Mexico.
- Source
- Arch Med Res, 1992 Aut, 23:3, 111-6
- Abstract
- An ethnobotanical study of plants used in Mexican traditional medicine was made. The source was the national inquiry done by the IMSS-COPLAMAR health program (1983-1985) in which the plants used to treat mental disorders were selected and analyzed, in order to select the most frequent botanical species used in traditional medicine as sedatives, anticonvulsants and hypnotics.
- Language of Publication
- English
- Unique Identifier
- 93385764
- MeSH Heading (Major)
- Hypnotics and Sedatives|IP/*TU; Mental Disorders|*DT; Plants, Medicinal|*/CL
- MeSH Heading
- Anticonvulsants|IP/TU; Human; Mexico; Nervous System|DE; Plant Extracts|IP/PD/TU
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0188-0128
- Country of Publication
- MEXICO
Record 11 from database: MEDLINE
- Title
- Medicinal plants used to treat malaria in Madagascar.
- Author
- Rasoanaivo P; Petitjean A; Ratsimamanga Urverg S; Rakoto Ratsimamanga A
- Address
- Institut Malgache de Recherches AppliquÆees, Antananarivo, Madagascar.
- Source
- J Ethnopharmacol, 1992 Sep, 37:2, 117-27
- Abstract
- Two-hundred thirty-nine Madagascan medicinal plants have been either retrieved from computerized ethnobotany information or identified in our own ethnomedicine work as having antimalarial properties. Such a high rate percent of plants compared to those used empirically to treat other diseases reflects the importance and the complication of this major tropical disease in Madagascar.
- Language of Publication
- English
- Unique Identifier
- 93061113
- MeSH Heading (Major)
- Antimalarials|*CH; Malaria|*DT; Plants, Medicinal|*/CH
- MeSH Heading
- Human; Madagascar
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 12 from database: MEDLINE
- Title
- Traditional medicinal plants used in the treatment of gastric ailments.
- Author
- Holdsworth D
- Address
- Source
- P N G Med J, 1978 Jun, 21:2, 175-83
- Abstract
- A recent paper discussed plants used in traditional medicine for fevers and malaria throughout Papua New Guinea (Holdsworth, 1975 a). This paper summarises information now available on plants used to treat gastric ailments, especially diarrhea and dysentery.
- Language of Publication
- English
- Unique Identifier
- 79017227
- MeSH Heading (Major)
- Gastrointestinal Diseases|*DT; Medicine, Traditional|*; Plants, Medicinal|*/AN
- MeSH Heading
- Alkaloids|AN; Diarrhea|DT; Dysentery|DT; Human; New Guinea
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0031-1480
- Country of Publication
- PAPUA NEW GUINEA
Record 13 from database: MEDLINE
- Title
- A review of plants used in the treatment of liver disease: part 1.
- Author
- Luper S
- Address
- Southwest College of Naturopathic Medicine: 2140 East Broadway Rd. Tempe, AZ 85282, USA. lupers@cwix.com
- Source
- Altern Med Rev, 1998 Dec, 3:6, 410-21
- Abstract
- Botanicals have been used traditionally by herbalists and indigenous healers worldwide for the prevention and treatment of liver disease. Clinical research in this century has confirmed the efficacy of several plants in the treatment of liver disease. Basic scientific research has uncovered the mechanisms by which some plants afford their therapeutic effects. Silybum marianum (milk thistle) has been shown to have clinical applications in the treatment of toxic hepatitis, fatty liver, cirrhosis, ischemic injury, radiation toxicity, and viral hepatitis via its antioxidative, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulating, and liver regenerating effects. Picrorhiza kurroa, though less well researched than Silybum, appears to have similar applications and mechanisms of action. When compared with Silybum, the hepatoprotective effect of Picrorhiza was found to be similar, or in many cases, superior to the effect of Silybum.
- Language of Publication
- English
- Unique Identifier
- 99072929
- MeSH Heading (Major)
- Antioxidants|PK/*TU; Liver Diseases|*TH; Plants, Medicinal|AE/*TU; Silymarin|PK/*TU
- MeSH Heading
- Glucosides|TU; Human; Medicine, Herbal; Plant Extracts|AE/TU
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 1089-5159
- Country of Publication
- UNITED STATES
- CAS Registry/EC Number
- 0 (Antioxidants); 0 (Glucosides); 0 (Plant Extracts); 22888-70-6 (Silymarin)
Record 14 from database: MEDLINE
- Title
- Parasitological and microbiological evaluation of Mixe Indian medicinal plants (Mexico).
- Author
- Heinrich M; Kuhnt M; Wright CW; Rimpler H; Phillipson JD; Schandelmaier A; Warhurst DC
- Address
- Institut fÂur Pharmazeutische Biologie, UniversitÂat, Freiburg, Germany.
- Source
- J Ethnopharmacol, 1992 Feb, 36:1, 81-5
- Abstract
- Medicinal plants are an important health resource in many regions of the Americas and are of particular importance to many Indian communities. Based on a recent ethnobotanical study in Mexico, we investigated the activity of 29 plant extracts against Entamoeba histolytica, three bacteria (Bacillus subtilis, Escherichia coli, and Micrococcus luteus) and two fungi (Cladosporium cucumerinum and Penicillium oxalicum). After separation of these extracts between CH2Cl2 and H2O the resulting phases were also evaluated.
- Language of Publication
- English
- Unique Identifier
- 92365398
- MeSH Heading (Major)
- Amebicides|*PD; Anti-Infective Agents|*PD; Antifungal Agents|*PD; Indians, Central American|*; Plant Extracts|*PD; Plants, Medicinal|*MI/*PS
- MeSH Heading
- Human; Medicine, Traditional; Mexico; Microbial Sensitivity Tests; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 15 from database: MEDLINE
- Title
- Survey of medicinal plants used as antimalarials in the Amazon.
- Author
- Brandão MG; Grandi TS; Rocha EM; Sawyer DR; Krettli AU
- Address
- LaboratÆorio de Farmacognosia, Faculdade de FarmÆacia, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
- Source
- J Ethnopharmacol, 1992 Apr, 36:2, 175-82
- Abstract
- Plants traditionally employed for the treatment of malaria in certain areas of Brazil, where this disease is prevalent, were surveyed by interviewing natives and migrants in the Amazon Region. Forty-one plants used for malarial treatment and/or for the related symptoms (fever and liver disorders) were collected and identified. Given the potential of Brazil's forests and medicinal plants, research on traditional plant-based remedies in this country may lead to the development of new drugs.
- Language of Publication
- English
- Unique Identifier
- 92301113
- MeSH Heading (Major)
- Antimalarials|PD/*TU; Malaria|*TH; Plants, Medicinal|*/CH
- MeSH Heading
- Animal; Brazil; Female; Human; Male; Mice; Plant Extracts|PD/TU; Plasmodium berghei|GD; Plasmodium falciparum|GD; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 16 from database: MEDLINE
- Title
- Development of natural crude drug resources from Taiwan (X). Pharmacognostical studies on the Chinese crude drug "han-lian-cao".
- Author
- Chen JY; Lin CC; Namba T
- Address
- School of Pharmacy, Kaohsiung Medical College, Taiwan.
- Source
- Am J Chin Med, 1992, 20:1, 51-64
- Abstract
- In a previous paper(1), it was reported that the drug "Han-lian-cao", in Taiwan was derived from the entire plant or aerial part of Eclipta prostrata L. and Alternanthera sessilis R. Brown. In this paper, the histological studies of "Han-lian-cao" derived from Wedelia and Hypericum plants, and of 3 species of Wedelia related plants distributed in Taiwan were made. The results showed that it was possible to classify these species by their external and internal characteristics. In addition, a key to the characteristics of the whole plants of Eclipta, Alternanthera, Wedelia and Hypericum plants are hereby given.
- Language of Publication
- English
- Unique Identifier
- 92296072
- MeSH Heading (Major)
- Botany|*; Plants, Medicinal|*AH/CL
- MeSH Heading
- Evaluation Studies; Human; Medicine, Chinese Traditional; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0192-415X
- Country of Publication
- UNITED STATES
Record 17 from database: MEDLINE
- Title
- Repertory of drugs and medicinal plants of Yemen.
- Author
- Fleurentin J; Pelt JM
- Address
- Source
- J Ethnopharmacol, 1982 Jul, 6:1, 85-108
- Abstract
- The traditional uses of plants for medicine were studied in the Yemen Arab Republic. To date, 130 medicinal plants have been identified and are presented in a table with the vernacular name, the geographical and ecological distribution, the medicinal use in Yemen and the pharmacological properties. Such a study of traditional medicine demonstrates the close relation between the medicinal plants and pathology.
- Language of Publication
- English
- Unique Identifier
- 82270539
- MeSH Heading (Major)
- Plants, Medicinal|*/CL
- MeSH Heading
- Human; Yemen
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 18 from database: MEDLINE
- Title
- Plants of Haiti used as antifertility agents.
- Author
- Weniger B; Haag Berrurier M; Anton R
- Address
- Source
- J Ethnopharmacol, 1982 Jul, 6:1, 67-84
- Abstract
- Haitian empirical medicine sprang from both European (16th to 19th century) and African (especially voodoo) traditional therapies. The use of medicinal herbs is highly developed. Our purpose was to list the plants held to be antifertility agents in the island. We identified about twenty species more or less currently used by the women as abortifacients or emmenagogues. The chemistry and active components of a few species are well-known. However, for most of them, some were partially studied, and no relation could be established between their chemical composition and their potential activities, and the rest are chemically unknown. We chemically screened extracts of Casearia ilicifolia, Eleutherine bulbosa, Rhoeo spathacea and Stemodia durantifolia, and identified flavonoids, triterpenes and sterols in the leaves of C. ilicifolia, and naphthoquinones, and a new anthraquinone, anthracene-9,10-dione-1,5-diol-4-methoxy-3-methyl-2-carboxylic acid methyl ester, in the bulbs of E, bulbosa. R. spathacea showed a stimulative activity on mouse uterus. Antifertility screening tests of C. ilicifolia and E. bulbosa showed activity in rats, but also probably toxicity.
- Language of Publication
- English
- Unique Identifier
- 82270538
- MeSH Heading (Major)
- Contraceptive Agents|*/IP; Plants, Medicinal|*/AN
- MeSH Heading
- Animal; Chemistry; Culture; Female; Haiti; Hormones|ME; Human; Magic; Mice; Ovum Implantation|DE; Oxytocics; Pregnancy; Rats; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 19 from database: MEDLINE
- Title
- The development of pharmacological and chemical research for application to traditional medicine in developing countries.
- Author
- Farnsworth NR
- Address
- Source
- J Ethnopharmacol, 1980 Jun, 2:2, 173-81
- Abstract
- The resolution of the 31st WHO Assembly requests: (1) a complete inventory of medicinal plants, (2) evaluation of efficacy and safety of the plants, (3) standardization of the plants. This involves a great effort, not only from developing but also from industrialized countries, being a task which will take many years and the full-time dedication of many researchers. Any research on the use of plants in traditional medicine should be developed in the framework of the activity of WHO. An example of this type of collaboration is the organization of research on fertility regulating plants in which six universities in different regions of th world are interested. This work must be done in such a way that industry should play a role, because of its greater knowledge of modern technologies, which may lead to a better utilization of plants and their extracts, and its funding and marketing abilities.
- Language of Publication
- English
- Unique Identifier
- 81097511
- MeSH Heading (Major)
- Developing Countries|*; Medicine, Traditional|*; Plants, Medicinal|*/CL
- MeSH Heading
- Animal; China; Health Planning; Human; Plant Extracts|CL; World Health Organization
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 20 from database: MEDLINE
- Title
- Medicinal plants of the eastern region of Madagascar.
- Author
- Novy JW
- Address
- Center for Conservation Biology, Department of Biological Sciences, Stanford, CA 94305-5020, USA.
- Source
- J Ethnopharmacol, 1997 Jan, 55:2, 119-26
- Abstract
- Sixty-eight plants used in the traditional medicinal practices of the Betsimisaraka and Tanala peoples of the eastern region of Madagascar are reported. Preparations and utilizations of these medicinal plants are as varied as the plants themselves. Some of the plants discussed are known to science, but because of the diversity of tribal groups in Madagascar, new preparations and utilizations of these plants were based on the ethnobotanical data collected from the Betsimisaraka and Tanala. Many of the plants discussed remain to be chemically tested. Ethnopharmacological information is in danger of being lost in Madagascar as slash and burn agriculture destroys much of the forest, and the elder traditional healers, often illiterate, pass away without handing down their knowledge.
- Language of Publication
- English
- Unique Identifier
- 97184855
- MeSH Heading (Major)
- Ethnobotany|*TD; Plants, Medicinal|*/CH/CL
- MeSH Heading
- Databases, Factual; Human; Madagascar; Medicine, Traditional; Support, U.S. Gov't, Non-P.H.S.
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- IRELAND
Record 21 from database: MEDLINE
- Title
- An examination of some reputed antifertility plants.
- Author
- Barnes CS; Price JR; Hughes RL
- Address
- Source
- Lloydia, 1975 Mar, 38:2, 135-40
- Abstract
- Solvent extracts prepared from 80 plant species reputed to show antifertility effects on human beings or from species closely related to such plants, showed no significant antifertility activity when fed to rats.
- Language of Publication
- English
- Unique Identifier
- 75174116
- MeSH Heading (Major)
- Contraceptives, Oral|*PD/TO; Plant Extracts|*; Plants|*; Plants, Medicinal|*/AN
- MeSH Heading
- Animal; Female; Fertility|DE; Human; Intubation, Gastrointestinal; Male; Plant Poisoning|MO; Reproduction|DE; Sex Behavior, Animal|DE; Species Specificity
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0024-5461
- Country of Publication
- UNITED STATES
Record 22 from database: MEDLINE
- Title
- Plants used in traditional medicine in eastern Tanzania. V. Angiosperms (Passifloraceae to Sapindaceae).
- Author
- Chhabra SC; Mahunnah RL; Mshiu EN
- Address
- Chemistry Department, Kenyatta University, Nairobi, Kenya.
- Source
- J Ethnopharmacol, 1991 May, 33:1-2, 143-57
- Abstract
- Sixty-one Angiosperms (Passifloraceae to Sapindaceae) are listed, which are used by traditional healers in five regions of Eastern Tanzania, namely, Coast, Dar es Salaam, Kilimanjaro, Morogoro and Tanga. For each species listed, the botanical name, vernacular name, collection number, locality, habit, distribution and medicinal uses are given. Additionally, information from the literature on medicinal uses, chemical constituents and pharmacological effects are also provided.
- Language of Publication
- English
- Unique Identifier
- 92047517
- MeSH Heading (Major)
- Medicine, Traditional|*; Plants, Medicinal|*/CH
- MeSH Heading
- Animal; Human; Tanzania
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 23 from database: MEDLINE
- Title
- Systematic and medicinal reasoning in Mitla folk botany.
- Author
- Messer E
- Address
- World Hunger Program, Brown University, Providence, RI 02912.
- Source
- J Ethnopharmacol, 1991 May, 33:1-2, 107-28
- Abstract
- This paper reviews cognitive, symbolic, systematic botanical, and biochemical bases of plant classification, and analyzes their interrelationships in the medicinal folk botany of Mitla, Oaxaca, Mexico. It evaluates the "pharmacological wisdom" of the local population, along with their symbolic use of the environment, to show how they construct medicinal plant classifications which follow a folk logic, but often conform as well to modern botanical classifications based on the principles of systematic botany or chemistry. Working from both the chemical data and the folk categories, the analysis suggests the local Zapotec population systematically selected plants which foam for symbolic reasons to treat illnesses of the "soul" and identifies their underlying chemical constituents and medicinal qualities. Other correspondences between chemical, medicinal and reputed folk qualities are also suggested.
- Language of Publication
- English
- Unique Identifier
- 92047513
- MeSH Heading (Major)
- Medicine, Traditional|*; Plants, Medicinal|*/CH
- MeSH Heading
- Animal; Culture; Human; Mexico; Support, U.S. Gov't, Non-P.H.S.
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 24 from database: MEDLINE
- Title
- Phytotherapeutic profile of Nigerian herbs. I: Anti-inflammatory and anti-arthritic agents.
- Author
- Iwu MM; Anyanwu BN
- Address
- Source
- J Ethnopharmacol, 1982 Nov, 6:3, 263-74
- Abstract
- From a survey of anti-arthritic remedies used in Igbo tribal ethnomedicine, three plants--Lonchocarpus cyanescens, Costus afar and Terminalia ivorensis--were selected for closer study. Twenty-five volunteers were monitored while receiving treatment from two reputable herbalists, and the result of the clinical investigation prompted the pharmacological and phytochemical studies on the herbs. Differential solvent extracts of the herbs reduced carragenin-induced oedema of the rat paw, checked diarrhoea due to arachidonic acid and castor oil, and ameliorated all signs associated with adjuvant-induced polyarthritis in rats. The constituent-activity relationship of the drugs and their probable mode of action are briefly discussed.
- Language of Publication
- English
- Unique Identifier
- 83113608
- MeSH Heading (Major)
- Anti-Inflammatory Agents|AN/*PD; Arthritis|*DT; Plants, Medicinal|*/AN
- MeSH Heading
- Aged; Animal; Arthritis, Adjuvant|DT; Chemistry; Diarrhea|CI/DT; Edema|CI/DT; Human; Mice; Middle Age; Nigeria; Rats
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 25 from database: MEDLINE
- Title
- Distribution and characterization of environmental promoter substances as assayed by synergistic Epstein-Barr virus-activating system.
- Author
- Ito Y; Tokuda H; Ohigashi H; Koshimizu K
- Address
- Source
- Princess Takamatsu Symp, 1983, 14:, 125-37
- Abstract
- The application of a new screening procedure which utilizes the synergistic effect of short-chain fatty acids and tumor-promoting diterpene esters enabled rapid and easy detection of environmental substances with Epstein-Barr virus (EBV)-activating/tumor-promoting potency. Over 500 samples were tested and more than 30 substances with such activities were identified. Most, if not all, were plant diterpene esters derived from Euphorbiaceae and Thymelaeaceae families and a few were indole alkaloids of microbial origin. We attempted to link these laboratory findings with those of epidemiological field studies on three virus-associated diseases, Burkitt's lymphoma, nasopharyngeal carcinoma, and adult T-cell leukemia/lymphoma, which are known to have a peculiar geographical distribution. Our hypothesis was that EBV-activating/tumor-promoting substances might be present in the abundant areas where such diseases are endemic. We noticed that many active diterpene ester-containing plants are widely used as herbal medicaments in Africa and China and determined many plant species that had such activities. One example is Aleurites fordii, a plant commonly grown in Southern China for industrial purposes which yielded a potent promoter substance (12-O-hexadecanoyl-16-hydroxyphorbol-13-acetate, HHPA). The active diterpene esters were purified and their possible mechanism was studied from the view of receptor-binding, protein kinase C activation and transmembrane signaling.
- Language of Publication
- English
- Unique Identifier
- 85104660
- MeSH Heading (Major)
- Carcinogens, Environmental|*AN; Herpesvirus 4, Human|*DE; Virus Activation|*DE
- MeSH Heading
- Animal; China; Diterpenes|AN; Enzyme Activation; Human; Mice; Plants|AN; Plants, Medicinal|AN; Protein Kinases|AN; Receptors, Immunologic|AN; Skin Neoplasms|CI
- Publication Type
- JOURNAL ARTICLE; REVIEW
- Country of Publication
- UNITED STATES
Record 26 from database: MEDLINE
- Title
- The use of herbal remedies in Jamaica.
- Author
- Michie CA
- Address
- Tropical Metabolism Research Unit, University Hospital, Kingston, Jamaica.
- Source
- Ann Trop Paediatr, 1992, 12:1, 31-6
- Abstract
- A survey of paediatric inpatients at the Tropical Metabolism Research Unit in the University Hospital, Kingston, Jamaica demonstrates that 71% had been treated with herbal remedies before their presentation to the medical services. The risks of the high prevalence of such medication in children are outlined, and two remedies in particular are highlighted because of their potential toxicity.
- Language of Publication
- English
- Unique Identifier
- 92296635
- MeSH Heading (Major)
- Medicine, Herbal|*; Plants, Medicinal|*/CL
- MeSH Heading
- Child; Child, Preschool; Female; Human; Infant; Jamaica; Kwashiorkor|TH; Male; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0272-4936
- Country of Publication
- ENGLAND
Record 27 from database: MEDLINE
- Title
- Chalcone tetramers, lophirachalcone and alatachalcone, from Lophira alata as possible anti-tumor promoters.
- Author
- Murakami A; Tanaka S; Ohigashi H; Hirota M; Irie R; Takeda N; Tatematsu A; Koshimizu K
- Address
- Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.
- Source
- Biosci Biotechnol Biochem, 1992 May, 56:5, 769-72
- Abstract
- Two chalcone tetramers were isolated as inhibitors of Epstein-Barr virus (EBV)-activation induced by a tumor promoter, teleocidin B-4, from a medicinal plant in tropical west Africa, Lophira alata (Ochnaceae). One of them was identified as lophirachalcone. The other, named alatachalcone, was new, and the structure was determined by spectral properties. Both compounds also showed potent inhibitory activities against teleocidin B-4-induced inflammation on mouse ear. In an initiation-promotion experiment on mouse skin, alatachalcone (16 nmol) significantly inhibited tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate (TPA, 1.6 nmol).
- Language of Publication
- English
- Unique Identifier
- 92330028
- MeSH Heading (Major)
- Anticarcinogenic Agents|*IP/TU; Chalcone|*AA/CH/IP/PD/TU; Phenols|CH/*IP/PD; Plant Extracts|*IP/TU
- MeSH Heading
- Animal; Antiviral Agents|IP/PD; Female; Herpesvirus 4, Human|DE; Inflammation|CI/DT; Irritants; Lyngbya Toxins; Macromolecular Systems; Mice; Mice, Inbred ICR; Plants, Medicinal|CH; Skin Neoplasms|CI/PC; Support, Non-U.S. Gov't; 9,10-Dimethyl-1,2-benzanthracene
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0916-8451
- Country of Publication
- JAPAN
Record 28 from database: MEDLINE
- Title
- Cytotoxicity of Fusarium species mycotoxins and culture filtrates of Fusarium species isolated from the medicinal plant Tribulus terrestris to mammalian cells.
- Author
- Abeywickrama K; Bean GA
- Address
- Department of Botany, University of Maryland, College Park.
- Source
- Mycopathologia, 1992 Dec, 120:3, 189-93
- Abstract
- Ayurvedic medicine, which uses decoctions made of medicinal plants, is used to cure diseases in many Asian countries including Sri Lanka. Although proper storage facilities for medicinal plants are unavailable in Sri Lanka, neither the potential for growth of toxigenic fungi nor their ability to produce mycotoxins in stored medicinal plants has been investigated. We isolated three Fusarium species, F. culmorum, F. acuminatum and F. graminearum from the medicinal plant Tribulus terrestris. Culture extracts of the 3 Fusarium spp. were cytotoxic to mammalian cell lines BHK-21 and HEP-2. Three toxic metabolites produced by Fusarium spp; T-2 toxin, zearalenone, and diacetoxyscirpenol were also cytotoxic to the mammalian cell lines. The 3 Fusarium spp. grown on rice media produced zearalenone. Plant material destined for medicinal use should be stored under suitable conditions to prevent growth of naturally occurring toxigenic fungi prior to its use.
- Language of Publication
- English
- Unique Identifier
- 93156795
- MeSH Heading (Major)
- Cytotoxins|AN/*TO; Fusarium|CH/*IP; Mycotoxins|AN/*TO; Plants, Medicinal|*MI
- MeSH Heading
- Animal; Cell Line; Chromatography, Thin Layer; Human
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0301-486X
- Country of Publication
- NETHERLANDS
Record 29 from database: MEDLINE
- Title
- Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum.
- Author
- Koumaglo K; Gbeassor M; Nikabu O; de Souza C; Werner W
- Address
- DÆepartement de Chimie, UniversitÆe du BÆenin, LomÆe, Togo.
- Source
- Planta Med, 1992 Dec, 58:6, 533-4
- Abstract
- The effects of three compounds, digitolutein (1), rubiadin 1-methyl ether (2) and damnacanthal (3) extracted from the stem bark and the roots of Morinda lucida Benth. on the growth of Plasmodium falciparum in vitro were investigated. The number of parasites (schizonts) decreased significantly in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms of each compound tested. The IC50 values were calculated.
- Language of Publication
- English
- Unique Identifier
- 93133958
- MeSH Heading (Major)
- Anthraquinones|CH/IP/*PD; Antimalarials|CH/*PD; Plants, Medicinal|*/CH; Plasmodium falciparum|*DE
- MeSH Heading
- Animal; Human; Molecular Structure; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0032-0943
- Country of Publication
- GERMANY
Record 30 from database: MEDLINE
- Title
- Lead poisoning from Indian herbal medicine (Ayurveda) [see comments]
- Author
- Dunbabin DW; Tallis GA; Popplewell PY; Lee RA
- Address
- Flinders Medical Centre, Bedford Park, Sa.
- Source
- Med J Aust, 1992 Dec, 157:11-12, 835-6
- Abstract
- OBJECTIVE: To present a case of lead poisoning following ingestion of Indian herbal medicine. CLINICAL FEATURES: A 37-year-old man presented with a history of abdominal pain, anorexia and malaise. He had recently returned from a trip to India where he had been taking two different herbal tonics. Investigation revealed low-grade hepatitis and normocytic anaemia with prominent basophilic stippling. The blood lead concentration was high, and analysis of the herbal tablets revealed a very high lead content. INTERVENTION AND OUTCOME: The patient required narcotic analgesia for abdominal pain and was treated with chelation therapy with calcium ethylenediaminetetra-acetate (calcium EDTA) for five days which resulted in a high urinary excretion of lead and resolution of his symptoms over a period of several days. CONCLUSION: Lead poisoning in Australia is usually the result of chronic industrial exposure, but practitioners should be aware of the possibility of poisoning from other domestic sources such as unglazed pottery, cosmetics and herbal remedies, especially those from Asia and India, in which lead may be present in high concentration. Patients from Asia who present with unexplained anaemia or abdominal symptoms should be asked about exposure to such sources.
- Language of Publication
- English
- Unique Identifier
- 93086568
- MeSH Heading (Major)
- Lead Poisoning|*ET; Medicine, Ayurvedic|*; Medicine, Herbal|*; Plants, Medicinal|*/CH
- MeSH Heading
- Adult; Arsenic|AN; Case Report; Human; Lead|AN; Male; Mercury|AN
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0025-729X
- Country of Publication
- AUSTRALIA
Record 31 from database: MEDLINE
- Title
- Ethnopharmacologic study of Chinese rhubarb.
- Author
- Peigen X; Liyi H; Liwei W
- Address
- Source
- J Ethnopharmacol, 1984 May, 10:3, 275-93
- Abstract
- This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity. It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata, e.g. Rheum palmatum, R. palmatum var. tanguticum, R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.
- Language of Publication
- English
- Unique Identifier
- 84269150
- MeSH Heading (Major)
- Medicine, Chinese Traditional|*; Medicine, Oriental Traditional|*; Plants, Medicinal|*/AN; Rhubarb|*/AN
- MeSH Heading
- Anthraquinones|AN; Cathartics; Chemistry; Human; Plant Extracts|PD; Stilbenes|AN
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 32 from database: MEDLINE
- Title
- Herbal remedies of the Maritime Indians: phytosterols and triterpenes of 67 plants.
- Author
- Hooper SN; Chandler RF
- Address
- Source
- J Ethnopharmacol, 1984 Apr, 10:2, 181-94
- Abstract
- The phytosterols and triterpenes of the non-saponifiable lipid fraction of 67 local plants, many of which are Micmac and Malecite medicinal plants, were determined by comparing their relative retention times with those of known compounds on three different gas liquid chromatography columns. Results have been tabulated to indicate relative amounts. For many of these plants, sterols and triterpenes do not constitute a major proportion of the plant. The predominant sterol was beta-sitosterol and the predominant triterpenes were usually alpha- and beta- amyrin . A number of undetermined triterpenes were detected, some in relatively large amounts.
- Language of Publication
- English
- Unique Identifier
- 84217894
- MeSH Heading (Major)
- Phytosterols|*AN; Plants, Medicinal|*AN; Triterpenes|*AN
- MeSH Heading
- Canada; Human; Indians, North American; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 33 from database: MEDLINE
- Title
- Chronic pulmonary hypertension--the monocrotaline model and involvement of the hemostatic system.
- Author
- Schultze AE; Roth RA
- Address
- Department of Pathology, College of Veterinary Medicine, University of Tennessee, Knoxville, USA.
- Source
- J Toxicol Environ Health B Crit Rev, 1998 Oct, 1:4, 271-346
- Abstract
- Monocrotaline (MCT) is a toxic pyrrolizidine alkaloid of plant origin. Administration of small doses of MCT or its active metabolite, monocrotaline pyrrole (MCTP), to rats causes delayed and progressive lung injury characterized by pulmonary vascular remodeling, pulmonary hypertension, and compensatory right heart hypertrophy. The lesions induced by MCT(P) administration in rats are similar to those observed in certain chronic pulmonary vascular diseases of people. This review begins with a synopsis of the hemostatic system, emphasizing the role of endothelium since endothelial cell dysfunction likely underlies the pathogenesis of MCT(P)-induced pneumotoxicity. MCT toxicology is discussed, focusing on morphologic, pulmonary mechanical, hemodynamic, and biochemical and molecular alterations that occur after toxicant exposure. Fibrin and platelet thrombosis of the pulmonary microvasculature occurs after administration of MCT(P) to rats, and several investigators have hypothesized that thrombi contribute to the lung injury and pulmonary hypertension. The evidence for involvement of the various components of the hemostatic system in MCT(P)-induced vascular injury and remodeling is reviewed. Current evidence is consistent with involvement of platelets and an altered fibrinolytic system, yet much remains to be learned about specific events and signals in the vascular pathogenesis.
- Language of Publication
- English
- Unique Identifier
- 98450117
- MeSH Heading (Major)
- Endothelium, Vascular|*DE/PA; Hemostasis|*DE; Hypertension, Pulmonary|BL/*CI/ET; Hypertrophy, Right Ventricular|BL/*CI/ET; Monocrotaline|*AA/AE/*TO
- MeSH Heading
- Animal; Disease Models, Animal; Human; Plants, Medicinal|AE; Plants, Toxic|AE; Rats; Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
- ISSN
- 1093-7404
- Country of Publication
- UNITED STATES
Record 34 from database: MEDLINE
- Title
- Artemisia tridentata (basin sagebrush) in the Southwestern United States of America: medicinal uses and pharmacologic implications.
- Author
- Kelley BD; Appelt JM; Appelt GD
- Address
- School of Pharmacy, University of Colorado, Boulder 80309.
- Source
- Int J Addict, 1992 Mar, 27:3, 347-66
- Abstract
- Artemisia tridentata (basin sagebrush) is discussed as a medicinal plant in the southwestern United States of America. Active constituents present in A. tridentata are listed, the pharmacologic implications of their presence are reviewed, and medicinal applications are tabulated. Further research to determine the status of A. tridentata as a medicinal plant is encouraged.
- Language of Publication
- English
- Unique Identifier
- 92225750
- MeSH Heading (Major)
- Plants, Medicinal|*/CH
- MeSH Heading
- Human; Medicine, Herbal; Plant Extracts|PD/TO/TU; Southwestern United States
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
- ISSN
- 0020-773X
- Country of Publication
- UNITED STATES
Record 35 from database: MEDLINE
- Title
- Medicinal plants used in some rural populations of Oaxaca, Puebla and Veracruz, Mexico.
- Author
- Zamora Martínez MC; de Pascual Pola CN
- Address
- Centro de Investigaciones Forestales y Agropecuarias del Distrito Federal, INIFAP, MÆexico.
- Source
- J Ethnopharmacol, 1992 Jan, 35:3, 229-57
- Abstract
- Within Mexico's floristic abundance, plants with curative properties are outstanding due to their popularity in handling several illnesses, a fact that becomes specially important for the social groups of the tropical regions. In this paper the results of an ethnobotanical study carried out in 57 rural populations from the Mexican states of Oaxaca, Veracruz and Puebla are presented; questionnaire and interview methods were applied, with special attention to the use of plants for medical purposes. The most relevant results were: the taxonomic determination of 237 vegetal species from which 399 curative products are obtained, in order to combat 57 illnesses, the most frequent of which are those related to the digestive system, the skin, the reproductive system and those of supernatural origin, which can only be treated by the use of plants in special ceremonies known as 'limpias', due to their peculiar condition.
- Language of Publication
- English
- Unique Identifier
- 92194760
- MeSH Heading (Major)
- Plant Extracts|*TU; Plants, Medicinal|*CL
- MeSH Heading
- Human; Medicine, Traditional; Mexico; Rural Health
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0378-8741
- Country of Publication
- SWITZERLAND
Record 36 from database: MEDLINE
- Title
- Chronic pulmonary hypertension--the monocrotaline model and involvement of the hemostatic system.
- Author
- Schultze AE; Roth RA
- Address
- Department of Pathology, College of Veterinary Medicine, University of Tennessee, Knoxville, USA.
- Source
- J Toxicol Environ Health B Crit Rev, 1998 Oct, 1:4, 271-346
- Abstract
- Monocrotaline (MCT) is a toxic pyrrolizidine alkaloid of plant origin. Administration of small doses of MCT or its active metabolite, monocrotaline pyrrole (MCTP), to rats causes delayed and progressive lung injury characterized by pulmonary vascular remodeling, pulmonary hypertension, and compensatory right heart hypertrophy. The lesions induced by MCT(P) administration in rats are similar to those observed in certain chronic pulmonary vascular diseases of people. This review begins with a synopsis of the hemostatic system, emphasizing the role of endothelium since endothelial cell dysfunction likely underlies the pathogenesis of MCT(P)-induced pneumotoxicity. MCT toxicology is discussed, focusing on morphologic, pulmonary mechanical, hemodynamic, and biochemical and molecular alterations that occur after toxicant exposure. Fibrin and platelet thrombosis of the pulmonary microvasculature occurs after administration of MCT(P) to rats, and several investigators have hypothesized that thrombi contribute to the lung injury and pulmonary hypertension. The evidence for involvement of the various components of the hemostatic system in MCT(P)-induced vascular injury and remodeling is reviewed. Current evidence is consistent with involvement of platelets and an altered fibrinolytic system, yet much remains to be learned about specific events and signals in the vascular pathogenesis.
- Language of Publication
- English
- Unique Identifier
- 98450117
- MeSH Heading (Major)
- Endothelium, Vascular|*DE/PA; Hemostasis|*DE; Hypertension, Pulmonary|BL/*CI/ET; Hypertrophy, Right Ventricular|BL/*CI/ET; Monocrotaline|*AA/AE/*TO
- MeSH Heading
- Animal; Disease Models, Animal; Human; Plants, Medicinal|AE; Plants, Toxic|AE; Rats; Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
- ISSN
- 1093-7404
- Country of Publication
- UNITED STATES
Record 37 from database: MEDLINE
- Title
- Inhibition of HIV replication by Hyssop officinalis extracts.
- Author
- Kreis W; Kaplan MH; Freeman J; Sun DK; Sarin PS
- Address
- Department of Medicine, North Shore University Hospital, Manhasset, NY 11030.
- Source
- Antiviral Res, 1990 Dec, 14:6, 323-37
- Abstract
- Crude extracts of dried leaves of Hyssop officinalis showed strong anti-HIV activity as measured by inhibition of syncytia formation, HIV reverse transcriptase (RT), and p17 and p24 antigen expression, but were non-toxic to the uninfected Molt-3 cells. Ether extracts from direct extraction (Procedure I), after removal of tannins (Procedure II), or from the residue after dialysis of the crude extract (Procedure III), showed good antiviral activity. Methanol extracts, subsequent to ether, chloroform and chloroform ethanol extractions, derived from procedure I or II, but not III, also showed very strong anti-HIV activity. In addition, the residual material after methanol extractions still showed strong activity. Caffeic acid was identified in the ether extract of procedure I by HPLC and UV spectroscopy. Commercial caffeic acid showed good antiviral activity in the RT assay and high to moderate activity in the syncytia assay and the p17 and p24 antigen expression. Tannic acid and gallic acid, common to other teas, could not be identified in our extracts. When commercial products of these two acids were tested in our assay systems, they showed high to moderate activity against HIV-1. Hyssop officinalis extracts contain caffeic acid, unidentified tannins, and possibly a third class of unidentified higher molecular weight compounds that exhibit strong anti-HIV activity, and may be useful in the treatment of patients with AIDS.
- Language of Publication
- English
- Unique Identifier
- 91207058
- MeSH Heading (Major)
- Antiviral Agents|*; HIV|AN/*DE; Plant Extracts|AN/*PD; Plants, Medicinal|*/AN; Virus Replication|*DE
- MeSH Heading
- Caffeic Acids|PD; Cell Fusion; Cells, Cultured; Chromatography, High Pressure Liquid; Human; HIV Antigens|AN; In Vitro; RNA-Directed DNA Polymerase|AN; Spectrophotometry, Ultraviolet; Support, Non-U.S. Gov't; Tannins|AN
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0166-3542
- Country of Publication
- NETHERLANDS
Record 38 from database: MEDLINE
- Title
- Evaluation of indigenous plants in the treatment of acute shigellosis.
- Author
- Haider R; Khan AK; Aziz KM; Chowdhury A; Kabir I
- Address
- International Centre for Diarrhoeal Disease Research, Bangladesh.
- Source
- Trop Geogr Med, 1991 Jul, 43:3, 266-70
- Abstract
- The clinical efficacy of three indigenous plants was compared with that of ampicillin and placebo in a randomized double blind clinical trial. Eighty-two men with shigellosis were studied. Sixteen patients received dried unripe fruit powder of 'bel' (Aegle marmelos), 19 received dried powdered plant of 'thankuni' (Hydrocotyle asiatica), 15 received a similar preparation of 'gandhavadulia' (Paederia foetida), 15 received ampicillin and 17 received a placebo. Treatment with indigenous plants did not show any clinical improvement or bacteriological cure as compared to ampicillin. The natural history of shigellosis was obtained by documenting the response of the indigenous plants and placebo treated groups.
- Language of Publication
- English
- Unique Identifier
- 92280033
- MeSH Heading (Major)
- Dysentery, Bacillary|*DT/MI/PP; Medicine, Ayurvedic|*; Plants, Medicinal|*PH
- MeSH Heading
- Adolescence; Adult; Aged; Ampicillin|TU; Bangladesh; Double-Blind Method; Feces|MI; Human; Male; Middle Age; Support, Non-U.S. Gov't
- Publication Type
- CLINICAL TRIAL; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
- ISSN
- 0041-3232
- Country of Publication
- NETHERLANDS
Record 39 from database: MEDLINE
- Title
- Repertory of standard herbal drugs in the Moroccan pharmacopoea.
- Author
- Be
