Valid 08/2001 - 10/2001
Sigma Chemical Co.
P.O. Box 14508
St. Louis, MO 63178 USA
Tel: 314-771-5765
             M A T E R I A L  S A F E T Y  D A T A  S H E E T
             
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
    CATALOG #:            P2126
    NAME:                 L-PHENYLALANINE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
    CAS #:    63-91-2
    MF: C9H11NO2
    EC NO:  200-568-1
  SYNONYMS
    L-ALANINE, PHENYL- * L-ALANINE, 3-PHENYL- * (S)-ALPHA-AMINO-
    BENZENEPROPANOIC ACID * (S)-ALPHA-AMINOHYDROCINNAMIC ACID * (S)-2-
    AMINO-3-PHENYLPROPANOIC ACID * (S)-ALPHA-AMINO-BETA-PHENYLPROPIONIC
    ACID * (S)-2-AMINO-3-PHENYLPROPIONIC ACID * ANTIBIOTIC FN 1636 *
    BENZENEPROPANOIC ACID, ALPHA-AMINO-, (S)- * HYDROCINNAMIC ACID, ALPHA-
    AMINO- * PHENYLALANINE * PHENYL-ALPHA-ALANINE * (-)-PHENYLALANINE * (-
    )-BETA-PHENYLALANINE * BETA-PHENYLALANINE * BETA-PHENYL-ALPHA-ALANINE
    * BETA-PHENYL-L-ALANINE * 3-PHENYL-L-ALANINE * L-PHENYLALANINE * L-(-)
    -PHENYLALANINE * L-BETA-PHENYLALANINE * (S)-PHENYLALANINE * (S)-(-)-
    PHENYLALANINE * 3-PHENYLALANINE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
    DATA NOT AVAILABLE
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
    IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
    CALL A PHYSICIAN.
    IF INHALED, REMOVE TO FRESH AIR. IF BREATHING BECOMES DIFFICULT,
    CALL A PHYSICIAN.
    IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS
    AMOUNTS OF WATER.
    IN CASE OF CONTACT WITH EYES, FLUSH WITH COPIOUS AMOUNTS OF WATER
    FOR AT LEAST 15 MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING
    THE EYELIDS WITH FINGERS. CALL A PHYSICIAN.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
  EXTINGUISHING MEDIA
    WATER SPRAY.
    CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
  SPECIAL FIREFIGHTING PROCEDURES
    WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
    PREVENT CONTACT WITH SKIN AND EYES.
  UNUSUAL FIRE AND EXPLOSIONS HAZARDS
    EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
    WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY
    RUBBER GLOVES.
    SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
    AVOID RAISING DUST.
    VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
    REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
    SAFETY SHOWER AND EYE BATH.
    MECHANICAL EXHAUST REQUIRED.
    AVOID INHALATION.
    AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
    AVOID PROLONGED OR REPEATED EXPOSURE.
    NIOSH/MSHA-APPROVED RESPIRATOR.
    COMPATIBLE CHEMICAL-RESISTANT GLOVES.
    CHEMICAL SAFETY GOGGLES.
    KEEP TIGHTLY CLOSED.
    STORE IN A COOL DRY PLACE.
    WASH THOROUGHLY AFTER HANDLING.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
  PHYSICAL PROPERTIES
    MELTING POINT:      270 - 275 C
    SOLUBILITY:
           WATER -Z26130
    PH:                      5.0 - 7.0
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
  STABILITY
    STABLE.
  INCOMPATIBILITIES
    STRONG OXIDIZING AGENTS
  HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
    CARBON MONOXIDE, CARBON DIOXIDE
    NITROGEN OXIDES
  HAZARDOUS POLYMERIZATION
    WILL NOT OCCUR.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
  ACUTE EFFECTS
    MAY CAUSE SKIN IRRITATION.
    MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.
    MAY CAUSE EYE IRRITATION.
    MAY BE HARMFUL IF INHALED.
    MATERIAL MAY BE IRRITATING TO MUCOUS MEMBRANES AND UPPER
    RESPIRATORY TRACT.
    MAY BE HARMFUL IF SWALLOWED.
    TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
    TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
  RTECS #: AY7535000
    ALANINE, PHENYL-, L-
  TOXICITY DATA
    IPR-RAT LD50:5287 MG/KG                       ABBIA4 58,253,1955
    IPR-MUS LD50:>1322 MG/KG                      YKKZAJ 97,1117,1977
  TARGET ORGAN DATA
    MATERNAL EFFECTS (UTERUS, CERVIX, VAGINA)
    SPECIFIC DEVELOPMENTAL ABNORMALITIES (CARDIOVASCULAR SYSTEM)
    ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
    (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
    COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
    DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
    DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
    CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
    OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
    CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
  REVIEWS, STANDARDS, AND REGULATIONS
    OEL=MAK
    NOES 1983: HZD X5534; NIS 4; TNF 792; NOS 14; TNE 19901; TFE 14903
    EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
    THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
    BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
    FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
    OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
    PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
    COPYRIGHT 2001 SIGMA-ALDRICH CO.
    LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY