MSM (a.k.a. Dimethyl Sulfone) is a naturally occurring form of organic sulphur found in all living organisms. It is present at a low concentration in human body fluids and tissue, and research suggests that a minimum concentration in the body may be critical both to normal function and also to structure.

MSM is found in many common foods, including milk, meat, fish, and a variety of fruits, vegetables and grains. However, when foods are processed, heated or dried, the essential MSM is readily lost. Therefore, unless a person's diet is composed primarily of milk and raw food, it is unlikely that he or she is receiving enough MSM for proper health.

Studies have suggested that the level of MSM in the body drops with increasing age. As you know, good health practices involve replacing essential substances that our bodies naturally use up or which, when ingested as supplements, show a mean residence time of only a few weeks. The most effective and convenient way to prevent a sulphur-deficient diet is to replenish the body's MSM with a regular dietary supplement.

MSM is an odorless, essentially tasteless, water-soluble, white, crystalline substance that serves as an important, bioavailable source of dietary sulphur. Sulphur plays an indispensable and unfortunately often overlooked role in human nutrition. It is an essential dietary component responsible for maintaining the conformation of the body's proteins by forming flexible disulfide bonds between certain amino acids. It has a critical role in maintaining the integrity of connective tissue. Thiol (i.e. sulphydryl) groups are vital for the catalytic function of many of the body's enzymes. To perform properly our bodies need a constant intake of easily available sulphur.

MSM has been marketed in the United States for the past eight years, and the results have been extraordinary. BioSynergy is one of the few North American producers of high purity MSM, and the sole manufacturer of Adaptin, a fine food grade purified MSM for human consumption.

Purified MSM can be applied topically in a gel or administered orally as the crystalline material. The subject of extensive research since 1979, MSM is of exceedingly low toxicity to all forms of plant and animal life. Acute, intermediate and long term studies indicate that MSM exhibits very low toxicity by any route of administration.

When incorporated into a gel or lotion and applied to the skin, purified MSM softens, smoothes, soothes, and makes older skin more pliable. The results have been quite remarkable. Except for its beneficial inhibitory effect on cross-linking collagen and proteins, whereby it reduces hardening of skin and connective tissue, MSM appears to be inert in tissues and body fluids. Because of inertness, MSM is non-allergenic and non-pyretic, and has no interfering or undesirable pharmacological effects.

Conditions that have responded favorably to oral doses of MSM include:

Allergenic Responses

MSM has a broad and profound effect in ameliorating diverse allergic responses. Subjects find a direct correlation between concentrations of MSM used in resistance allergens. MSM physically protects against many allergens by competing for mucous membrane receptor sites, and is widely considered one of the most important anti-allergenic substances since anti-histamines were introduced more than four decades ago.

Environmental allergies: Subjects with chronic severe allergies to environmental materials such as house dust, pollen, wool, animal hair, feathers and other allergens report substantial relief from their allergic symptoms.

Food and drug allergies: Individuals who manifest an allergic response to drugs, non-steroidal anti-arthritic agents, and oral antibiotics, as well as those who are mildly to severely allergic to various foods (e.g. cereals, seafood, milk, etc.) report either a lessened intolerance or a complete tolerance to these substances.

Pain from Systemic Inflammatory Disorders

Individuals presenting symptoms of pain and inflammation associated with injuries and various musculoskeletal disorders reported substantial and long lasting relief. Most, trying first MSM alone, then in combination with ascorbic acid, reported greater benefit with the combination. Athletes have used MSM to relieve stiffness and the pain of strained or sore muscles associated with physical stress.

Gastrointestinal Upset

MSM is effective in ameliorating gastrointestinal upset, such as that produced by parasitic infection or the ingestion of certain pharmaceuticals. Individuals with gastrointestinal symptoms, including diarrhea, chronic constipation, nausea, hyperacidity and/or epigastric pain, or inflammation of mucous membranes have also experienced dramatic relief.

Parasitic Infections

In vitro and in vivo tests suggest that MSM has activity against a variety of medically important parasitic problems of the intestinal and urogenital tracts. For example, MSM is active against Giardia lamblia (traveler's diarrhea"), Trichomonads and round worms. It may affect such infections by competing for binding sites at the mucous membrane surface, presenting a blocking interface between host and parasite. MSM and Your Company

As a new ingredient to you, MSM offers many exciting possibilities. It has been proven exceptionally safe and effective and, as research continues, even more beneficial properties are likely to be discovered. We believe it is only a matter of time before the public at large becomes aware of MSM, realizes its relief-giving potential, and starts to demand products containing this important source of organic sulphur.

BioSynergy Nutriceuticals can supply you with high-quality bulk MSM for use in lotions or gels, or for oral applications. Adaptin Fine Food Grade MSM is available in 25 kg drums and is exclusively available from BioSynergy.

We believe that MSM is one of the most significant discoveries of the late 20th century. As the new millennium approaches, and the popularity of MSM increases among researchers and consumers, you owe it to your company and to your customers to consider incorporating MSM into your product line.

Please do not hesitate to contact us with any questions you may have regarding Adaptin Methylsulfonylmethane and the opportunities it can provide for good health - both physically and financially. We look forward to talking with you shortly about this amazing opportunity.