Germanium

Here is a table of scientific studies which include references to the organic substance called carboxyethyl germanium sesquioxide. This substance was "discovered" and then synthesized by Dr. Kazuhiko Asai, who lived in Japan many years ago. He wrote THE book, entitled "Miracle Cure Organic Germanium," published in English by Japan Publications, Inc., copyrighted in 1980, LCCC No. 79-91512, ISBN: 0-57040-474-3.

Karl's book was published by Life Extension Educational Service in 1987, Second Edition, (now out of print).

The table below contains the title of the 39 various scientific studies as well as a link to that study on this page.

You'll probably find that this is the only source of scientific information about germanium available on the Internet.

Keep in mind that the ONLY form of germanium for which any anti-cancer claims are made is, technically, germanium carboxyethyl sesquioxide. I have included studies, below, on "germanium oxide" which is the most common form of germanium. Germanium oxide is not very toxic -- it takes a dose of about 2 pounds to kill a mouse! But, the FDA has banned the importation of carboxyethyl germanium sesquioxide into the US, probably instigating "studies" which would show that "germanium" (actually germanium oxide) caused cancer. These would be spurious references to criticize the true form of germanium which Dr. Asai developed and researched in Japan.

Number	Official Title of the Study	Comments
...1...	Mutagenicity, carcinogenicity and teratogenicity of germanium compounds.	"Germanium is not carcinogenic and even appears to inhibit cancer development and, in the form of the organic germanium compound, spirogermanium, to destroy cancer cells."
...2...	Hazard assessment of germanium supplements.	Here is one of those fraudulent "studies" actually done by the US Government, claiming toxicity for "germanium."
...3...	Effects of germanium oxide and other chemical compounds on phenylmercury acetate-induced genotoxicity in cultured human lymphocytes.	Another study showing "dangers." Note the reference to "germanium oxide" -- not the form recommended by Dr. Asai or sold by Vibrant Life
...4...	Multidisciplinary treatment of head and neck cancer using BCG, OK-432, and GE-132 as biologic response modifiers.
...5...	Germanium intoxication with sensory ataxia.	Another study on "inorganic germanium" -- which is NOT the one you want.
...6...	Applications of a self-collimating BGO detector system to radiological emergency response.
...7...	Germanium-induced nephropathy: report of two cases and review of the literature.	Another study of "germanium oxide." Germanium oxide can be hidden, with vitamin C, and sold as "germanium sesquioxide" as a fraud.
...8...	Inhibitory effects of Ge-132 (carboxyethyl germanium sesquioxide) derivatives on enkephalin-degrading enzymes.
...9...	Phase I trial of spirogermanium given by infusion in a multiple-dose schedule.
..10...	Phase II study of spirogermanium in advanced ovarian malignancy.
..11...	Phase I clinical trial of spirogermanium.
..12...	Therapeutic effects of organic germanium.	"Germanium is present in all living plant and animal matter in micro-trace quantities. Its therapeutic attributes include immuno-enhancement, oxygen enrichment, free radical scavenging, analgesia and heavy metal detoxification. Toxicological studies document Germanium's rapid absorption and elimination from the body, and its safety. Clinical trials and use in private practices for more than a decade have demonstrated Germanium's efficacy in treating a wide range of serious afflictions, including cancer, arthritis and senile osteoporosis. Germanium's anti-viral and immunological properties, including the induction of interferon, macrophages, T-suppressor cells and augmentation of natural killer cell activity, suggest its possible efficacy in treating and/or preventing AIDS. "
..13...	Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): an Eastern Cooperative Oncology Group study
..14...	Tubulointerstitial nephropathy persisting 20 months after discontinuation of chronic intake of germanium lactate citrate.
..15...	Abuse of germanium associated with fatal lactic acidosis.	Another study done with inorganic germanium -- a fraud.
..16...	Inhibition by germanium oxide of the mutagenicity of cadmium chloride in various genotoxicity assays.
..17...	Effects of proxigermanium on interferon production and 2',5'-oligoadenylate synthetase activity in the lung of influenza virus-infected mice and in virus-infected human peripheral blood mononuclear cell cultures.
..18...	Germanium myopathy: clinical and experimental pathological studies.	Another misleading study
..19...	Renal failure caused by long-term use of a germanium preparation as an elixir.	Another study of "inorganic" germanium. These dangerous forms were deliberately spread in Japan, to cause death, so that the FDA could then claim that ALL germanium was deadly, and thus ban import of this cancer-fighting agent.
..20...		Identification of synergistic combinations of spirogermanium with 5-fluorouracil or cisplatin using a range of human tumour cell lines in vitro.
Menu Choice #20
..21...	A Phase I trial of spirogermanium administered on a continuous infusion schedule.
..22...	Nephrotoxicity of germanium compounds: report of a case and review of the literature
..23...	Spirogermanium: a new investigational drug of novel structure and lack of bone marrow toxicity.
..24...	Phase I study of spirogermanium given daily.
..25...	Nephrotoxicity and neurotoxicity in humans from organogermanium compounds and germanium dioxide.
..26...	Identification of 241Am in the axillary lymph nodes with an intrinsic germanium detector.
..27...	Performance of an array of large-volume germanium detectors for whole-body counting.
..28...	Germanium poisoning: clinical symptoms and renal damage caused by long-term intake of germanium.
..29...	Nephrotoxicity in humans by the ultratrace element germanium.
..30...	Cytotoxic effects and biological activity of 2-aza-8-germanspiro[4,5]-decane-2-propanamine- 8,8-diethyl-N,N-dimethyl dichloride (NSC 192965; spirogermanium) in vitro.
..31...	Determination of germanium and some other elements in hair, nail, and toenail from persons exposed and unexposed to germanium.
..32...	Rotating laminar emission camera with GE-detector: an analysis.
..33...	Rotating laminar emission camera with GE-detector: experimental results.
..34...	Rotating laminar emission camera with GE-detector: experimental results.
..35...	A phase II study of spirogermanium in advanced human malignancy.
..36...	Accumulation of germanium in the tissues of a long-term user of germanium preparation died of acute renal failure.
..37...	A phase II study of spirogermanium as second line therapy in patients with poor prognosis lymphoma. An NCI Canada Clinical Trials Group Study.
..38...	A phase II study of spirogermanium in patients with metastatic malignant melanoma. An NCI Canada Clinical Trials Group Study.	The required dose for treating cancer with the real germanium is about 2,000 mg per day. This study does not show how much was used -- typically these fraudulent studies use a low dose or a different substance.
..39...	Germanium dioxide-induced nephropathy: a new type of renal disease.

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