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Coenzyme Q10

is an enzyme that your heart really likes.

I remember "hearing about" CoQ10 for years and not doing anything about it.

Then I listened to a couple recorded lectures about CoQ10 and vowed that I would never again go through a day without taking some.

It was at that time that I developed the concept of the three different reasons for taking ANY vitamin.  In the past I had felt that I would take a vitamin only when I could notice a difference in how I felt.   But, from what I learned about CoQ10, I could not expect to feel any difference when I took it.  But, what I learned about made it seem so important that I resolved to take it despite the fact that I wouldn't feel any effect of taking it.

So, here is part of that story, about coenzyme Q10.



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Results for your query:
Words in title only: CoQ10
Published in 1957 through 1999
Only select references with abstracts available
Show references published in English only
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With an article type of: REVIEW

Documents: 1 to 2 of 2

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1 Hodges S, et al; CoQ10: could it have a role in cancer management? (Biofactors, 1999, Abstract available) [MEDLINE]
2 Langsjoen PH, et al; Overview of the use of CoQ10 in cardiovascular disease. (Biofactors, 1999, Abstract available) [MEDLINE

Record 1 from database: MEDLINE
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Title
CoQ10: could it have a role in cancer management?
Author
Hodges S; Hertz N; Lockwood K; Lister R
Address
University of Sheffield, UK.
Source
Biofactors, 1999, 9:2-4, 365-70
Abstract
Coenzyme Q10 or ubiquinone has been shown to have both anti-cancer and immune system enhancing properties when tested in animals. Preliminary results reported here suggest that it might inhibit tumour-associated cytokines. Clinical studies conducted with combination therapies of CoQ10 and other antioxidants are ongoing, but the results are difficult evaluate owing to the lack of proper control groups and of initial randomisation. Also on the basis of some anti-cancer effects of antioxidants reported in literature, further animal studies and a proper clinical trial of coenzyme Q10 in cancer patients are needed.
Language of Publication
English
Unique Identifier
99344543

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MeSH Heading (Major)
Anticarcinogenic Agents|*; Antineoplastic Agents|*; Antioxidants|*TU; Neoplasms|*DT; Ubiquinone|*AA/TU
MeSH Heading
Animal; Clinical Trials; Cytokines|AI; Human

Publication Type
JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL
ISSN
0951-6433
Country of Publication
NETHERLANDS

Record 2 from database: MEDLINE
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Title
Overview of the use of CoQ10 in cardiovascular disease.
Author
Langsjoen PH; Langsjoen AM
Address
 
Source
Biofactors, 1999, 9:2-4, 273-84
Abstract
The clinical experience in cardiology with CoQ10 includes studies on congestive heart failure, ischemic heart disease, hypertensive heart disease, diastolic dysfunction of the left ventricle, and reperfusion injury as it relates to coronary artery bypass graft surgery. The CoQ10-lowering effect of HMG-CoA reductase inhibitors and the potential adverse consequences are of growing concern. Supplemental CoQ10 alters the natural history of cardiovascular illnesses and has the potential for prevention of cardiovascular disease through the inhibition of LDL cholesterol oxidation and by the maintenance of optimal cellular and mitochondrial function throughout the ravages of time and internal and external stresses. The attainment of higher blood levels of CoQ10 (> 3.5 micrograms/ml) with the use of higher doses of CoQ10 appears to enhance both the magnitude and rate of clinical improvement. In this communication, 34 controlled trials and several open-label and long-term studies on the clinical effects of CoQ10 in cardiovascular diseases are reviewed.
Language of Publication
English
Unique Identifier
99344530

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MeSH Heading (Major)
Antioxidants|*TU; Cardiovascular Diseases|*DT; Ubiquinone|*AA/TU
MeSH Heading
Clinical Trials; Coronary Artery Bypass; Heart Failure, Congestive|DT; Human; Hypertension|DT; Myocardial Ischemia|DT; Reperfusion Injury|DT; Ventricular Dysfunction, Left|DT

Publication Type
JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
ISSN
0951-6433
Country of Publication
NETHERLANDS

 

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