DR. WEISS RECOMMENDS IPRIFLAVONE AND THE NATURAL MODEL OF MEDICINE INSTEAD OF DRUGS LIKE FOSOMAX™ FOR PREVENTION AND TREATMENT OF BONE LOSS

HERE IS WHY…

   Why is it the highest calcium consuming country in the world has the highest rate of osteoporosis? If the answer were to just take more calcium the problem would have been solved a long time ago. Before tackling that issue lets look at the numbers. As of 1990, twenty million women in the United States suffered from osteoporosis at a cost of 10 billion dollars and rising.[1]^,[2] In 1990, greater than 1.5 million fractures were reported worldwide.² Two thirds of these fractures occurred in women who were at particular risk for both osteopenia (a less dangerous form of bone loss which may develop into full osteoporosis) and osteoporosis. The risk tends to increase as women approach and pass menopausal years with one out of every five American women over the age of 65 having fractured one or more bones. The current numbers show that we are not making progress in the battle against osteoporosis, so what is medicine doing incorrectly? Let’s start with a look at Asia.

ASIAN WOMEN HAVE A FAR LOWER RATE OF OSTEOPOROSIS THAN AMERICAN WOMEN

   It is sad but true, that one of the most technologically advanced countries in the world has a greater incidence of bone fracture, osteopenia, and osteoporosis than most of Asia. What is going on? I think the question can be answered in two parts; what Asian women are not doing, and what they are doing.

ASIAN WOMEN ARE NOT CREATING BONE LOSS THROUGH THE FOODS THEY EAT

   Asian women live mostly on vegetables, a little fruit, and soybeans and are not exposed to refined white flour, white sugar, sparkling water, and excessive red meat that modern research demonstrates reduces bone density thus creating fractures and osteoporosis. Research demonstrates that for every 1-gram increase in animal protein, there will be a 1.75 mg loss of calcium in the urine. In addition, a great many Asian women eat a vegetarian diet, which is the preferred diet to retain healthy bone.[3]^,[4]    In America, we are literally eating our bones away with poor food choices.

ASIAN WOMEN ARE SUBSTITUTING PLANT PROTEIN (SOY) FOR ANIMAL PROTEIN AND EXERCISING AS WELL

   A great portion of Asian women have never sat at a table and eaten steak or even a croissant. They “eat to live” rather than “live to eat”, which explains the high consumption of soybeans. They are inexpensive, and readily available. They are high in protein (rarer in plant than animal species) and contain thousands of beneficial compounds. In addition, Asian women are exercising. In Asia martial arts are often performed an hour a day before the workday. In addition, many work higher labor jobs requiring more physical exertion. In science we have seen evidence that pounding type exercises like aerobics, running, weight lifting and others help retain bone mass.

HOW DOES SOY WORK AND WHAT IS IPRIFLAVONE?

   Soy has an indirect impact on calcium levels by enhancing calcium retention. Research has found that the sulfur-containing amino acids present in soy change the pH of the body’s system in a positive way so we retain calcium. This ability is particularly important, as bones are continuously in a state of turnover and remodel. This turnover allows new healthy strong bone to form and old bone to be recycled. It has been shown that 7,000 milligrams of calcium enter and exit the bone every day. The amount and type of calcium will dictate if it is to be reabsorbed after leaving bone, or excreted in the urine. Soy is not only a good source of calcium but decreases urinary calcium (allowing it to be reabsorbed).[5]

   Ipriflavone is created by synthesizing the naturally occurring isoflavones from soybeans. It is these isoflavones which contain phytoestrogens believed to preserve bone mass.[6]^,[7] The role of isoflavones has been demonstrated in both human and animal research, with the results showing not only increasing bone mass, but fewer fractures. [8]^,[9]

IPRIFLAVONE VERSUS THE MEDICATION FOSOMAX™

   I cannot tell a lie, I do not believe in Fosomax.™ This is a drug originally derived from common soap scum, and it increases bone mass by preventing the naturally occurring recycling of the bone. It has not been shown in research to decrease fractures, although it does increase bone mass. This may be due to the fact that we are not renewing our bones to young strong healthy tissue, but are just keeping the old bone around, which may be weaker thus allowing fractures. In addition, there are two disturbing things about Fosomax™; it can burn the esophagus, and it mostly will not leave the body. There has not been research done on the long-term effects of either of these effects on the body. If you are currently on this medication, I recommend you see the prescribing doctor, and ask his or her opinion. Feel free to bring this article!

NATURE’S DISTRIBUTORS BRINGS YOU IPRIFLAVONE IN TWO WAYS!

   If you are an at-risk person who is already taking a calcium supplement that you are happy with, then I recommend the following: 200 mg of Ipriflavone three times daily between meals.

   In addition, we have brought you the latest in research in one easy formula we call Osteo-Bones™ which already has the Ipriflavone included. The dosage is:

Osteo-Bones two to four times daily with meals.

WHO IS AT RISK AND WHEN SHOULD I START TAKING CALCIUM AND IPRIFLAVONE?

   At risk people are generally peri-menopausal females and senior citizens. If you are a female age 45 or older I recommend a hip dexa test, which will accurately tell you if you are at risk. Even if that test is negative I still have all my female patients who are around menopause years on some form of calcium and soy. If the test is positive for either osteopenia or osteoporosis, then I have my patients take the Osteo-Bones[10].

[1] Riggs BL. (1990) A new option in treating osteoporosis NEJM 323:124-5

[2] Licata AA. (1994) prevention and osteoporosis management. Cleveland Clin J Med 61: 451-60

[3] Abelow BJ, Holford TR, Insogna KL. (1992) Cross-cultural association between dietary animal protein and hipfracture: a hypothesis. Calcif Tissue Int  50:14-18

[4] Messina M, Messina V, Setchell K. (1994) The simple soybean and your health. Garden City Park, NY: Avery Publishing

[5] Breslau NA, Brinkly L, Hill KD, Pak CYC. (1988) Relationship of animal protein-rich diet to kidney stone formation and calcium metabolism. J Clin Endocrinol Metab 66:140-6

[6] Brandi ML. (1992) Flavanoids: biochemical effects and therapeutic applications. Bone Min 19 (suppl): S3-S14

[7] Arjmandi BH, Alekel L, Hollis BW, Amin D, Stacewicz-Sapuntzakis M, Guo P. (1966) Dietary soybean protein prevents bone loss in ovariectomized rat model. J Nutr 125:799S.

[8] Anderson JJ, Ambrose WW, Garner SC. (1995) Orally dosed genestein from soy and prevention of cancallous bone loss in two ovariectomized rat models. J Nutr  125:799S

[9] Potter SM, Baum JA, Teng H, Stillman RJ, Erdman JW. (1998) Soy protein and isoflavones: their effects on blood lipids and bone mineral density in post menopausal women. Am J Clin Nutr (in press)

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